BACKGROUND Earlier work from our laboratory highlighted the therapeutic potential of
curcumin (turmeric), used as a dietary ingredient and as a natural anti‐inflammatory agent in …

Objectives. Cellular senescence is a unique cellular response pathway thought to be closely
associated with the aging process. The senescent phenotype is characterized by the loss of …

PURPOSE: We report contemporary outcomes of salvage cryoablation at a large number of
centers which have participated in the COLD (Cryo On-Line Data) Registry. MATERIALS …

OBJECTIVES: Owing to the ability to better detect small-volume tumors, we have seen an
increasing population of men with low-risk unifocal prostate cancer. We report our safety and …

PURPOSE: We report the largest data set to date to our knowledge regarding outcomes for
primary whole gland prostate cryoablation. MATERIALS AND METHODS: The COLD (Cryo …

Objectives. Angiogenesis is believed to play an important role in tumor progression and
metastasis. Previous studies have suggested that the microvessel density (MVD) of prostate …

Objective. Because up to 40 percent of surgically treated patients with prostate cancer are
subsequently found to be clinically understaged, a more sensitive staging modality to identify …

Neuroendocrine (NE) cells are enigmatically found in association with human prostate cancers
and their numbers are reported to increase in advanced and hormoneresistant tumors. …

The tropical shrub, Rauwolfia vomitoria, is a medicinal plant used traditionally to treat a
variety of ailments. A bioactive β-carboline alkaloid, alstonine, present in this extract was …

Although genomic research has predominantly relied on phenotypic ascertainment of
individuals affected with heritable disease, the falling costs of sequencing allow consideration of …