Despite the recent negative attention, mortgage securitization provides a vehicle to take
assets without much investor appeal and create bonds whose risk and return profiles are …

Data is the lifeblood of the securitization industry, and the lack of ready access to it and
proper tools to analyze it was considered to be a primary flaw in the recent credit crisis. This …

Background Patients with advanced midgut neuroendocrine tumors who have had disease
progression during first-line somatostatin analogue therapy have limited therapeutic options. …

Zinc (Zn 2+ ) is the most abundant biological metal ion aside from iron and is an essential
element in numerous biological systems, acting as a cofactor for a large number of enzymes …

Vacuolar-proton ATPases (V-ATPases) are conserved complexes that couple the hydrolysis
of ATP to the pumping of protons across membranes. V-ATPases are known to play diverse …

Importance The Canadian Cancer Trials Group study HN.6 is the largest randomized
clinical trial to date comparing the concurrent administration of anti–epidermal growth factor …

Background Previous catheter-based renal denervation studies have reported variable
efficacy results. We aimed to evaluate safety and blood pressure response after renal …

Background Previous randomised renal denervation studies did not show consistent efficacy
in reducing blood pressure. The objective of our study was to evaluate the effect of renal …

Purpose Neuroendocrine tumor (NET) progression is associated with deterioration in quality
of life (QoL). We assessed the impact of 177 Lu-Dotatate treatment on time to deterioration …

Background Catheter-based renal denervation has significantly reduced blood pressure in
previous studies. Following a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL Pivotal…