Extracellular vesicles are thought to facilitate pathogen transmission from arthropods to
humans and other animals. Here, we reveal that pathogen spreading from arthropods to the …

Tissue regeneration is vital to the form and function of an organ. At the core of an organs’
ability to self-renew is the stem cell, which maintains homeostasis, and repopulates injured or …

The Hippo pathway is an evolutionary conserved signaling network that regulates essential
processes such as organ size, cell proliferation, migration, stemness and apoptosis. …

Background Robust data on patient-reported outcome measures comparing treatments for
clinically localized prostate cancer are lacking. We investigated the effects of active monitoring…

Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified
more than 100 prostate cancer (PrCa)-susceptibility loci. We meta-analyzed genotype data …

The androgen receptor (AR) regulates prostate cell growth in man, and prostate cancer is the
commonest cancer in men in the UK. We present a comprehensive analysis of AR binding …

Prostate cancer is a highly heritable disease with large disparities in incidence rates across
ancestry populations. We conducted a multiancestry meta-analysis of prostate cancer …

… In examining reactions to certain high-profile deaths, the articles by Barry, Thomas and Mole
… His draft submission has been edited by Elizabeth Barry, and we are pleased to be able to …

… reader in cancer studies1, Kerry Avery research fellow and NIHR post-doctoral award
holder2, David E Neal professor of surgical oncology4, Freddie C Hamdy professor of surgery5 …

Importance Prostate cancer screening remains controversial because potential mortality or
quality-of-life benefits may be outweighed by harms from overdetection and overtreatment. …