Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipne ER, and angiotensin …

AI Goldberg, MC Dunlay, CS Sweet - The American journal of cardiology, 1995 - Elsevier
This report presents data on the safely and tolerabilify of losartan potassium (losartan), a
selective antagonist of the angiotensin II AT-1 receptor, in approximately 2,900 hypertensive …

A randomized, placebo-controlled, double-blind, parallel study of various doses of losartan potassium compared with enalapril maleate in patients with essential …

…, LS Ikeda, EB Nelson, DB Snavely, CS Sweet - …, 1995 - Am Heart Assoc
The efficacy and safety of various doses of losartan potassium, a specific and selective
angiotensin II receptor antagonist, were compared with those of placebo and enalapril maleate …

[HTML][HTML] Regulation of the cyanide-resistant alternative oxidase of plant mitochondria: identification of the cysteine residue involved in α-keto acid stimulation and …

DM Rhoads, AL Umbach, CR Sweet… - Journal of Biological …, 1998 - ASBMB
The cyanide-resistant alternative oxidase of plant mitochondria is a homodimeric protein
whose activity can be regulated by a redox-sensitive intersubunit sulfhydryl/disulfide system …

YopJ targets TRAF proteins to inhibit TLR‐mediated NF‐κB, MAPK and IRF3 signal transduction

CR Sweet, J Conlon, DT Golenbock… - Cellular …, 2007 - Wiley Online Library
The Yersinia pestis virulence factor YopJ is a potent inhibitor of the NF‐κB and MAPK
signalling pathways, however, its molecular mechanism and relevance to pathogenesis are the …

Heterocyclic analogs of the antihypertensive. beta.-adrenergic blocking agent (S)-2-[3-(tert-butylamino)-2-hydroxypropoxy]-3-cyanopyridine

…, JG Atkinson, BK Wasson, CS Sweet… - Journal of medicinal …, 1980 - ACS Publications
The syntheses of a series of isoelectronic analogues of (S)-2-[3-(ferf-butylamino)-2-hydroxypropoxy]-3-cyanopyridine
(1) are described; included in this group are examples of thiazole, …

Effects of losartan on a background of hydrochlorothiazide in patients with hypertension

…, JH Pratt, B Wiens, AI Goldberg, CS Sweet - …, 1995 - Am Heart Assoc
The purpose of this multicenter trial was to compare the antihypertensive efficacy and safety
of losartan potassium (losartan), a selective angiotensin II receptor antagonist, when added …

Losartan and low-dose hydrochlorothiazide in patients with essential hypertension: a double-blind, placebo-controlled trial of concomitant administration compared …

…, AI Goldberg, SM Snapinn, CS Sweet - Archives of Internal …, 1996 - jamanetwork.com
Background: Angiotensin II acts at the cellular level through specific angiotensin II subtype I,
AT-1 receptors. Losartan is the first of a new class of antihypertensive agents that …

Efficacy and tolerability of losartan potassium and atenolol in patients with mild to moderate essential hypertension

…, SE Keller, L Makris, AI Goldberg, CS Sweet… - American journal of …, 1995 - Elsevier
The objective of this study was to compare the antihypertensive efficacy and tolerability of
losartan potassium (losartan) and atenolol in patients with mild-to-moderate essential …

[PDF][PDF] Effect of N-[(S)-1-carboxy-3-phenylpropyl]-L-Ala-L-Pro and its ethyl ester (MK-421) on angiotensin converting enzyme in vitro and angiotensin I pressor …

DM Gross, CS Sweet, EH Ulm, EP Backlund… - … of Pharmacology and …, 1981 - Citeseer
ABSTRACT Gross, Dennis M., Charles S. Sweet, Edgar H. UIm, Elizabeth p. BackIund,
Audrey A. Morris, David WeItZ, Dennis L. Bohn, Herbert C. Wenger, Theodore C. Vaseil and …

[HTML][HTML] Activation of the plant mitochondrial alternative oxidase: insights from site-directed mutagenesis

AL Umbach, MA Gonzàlez-Meler, CR Sweet… - … et Biophysica Acta (BBA …, 2002 - Elsevier
The homodimeric cyanide-resistant alternative oxidase of plant mitochondria reduces
oxygen to water without forming ATP. Arabidopsis thaliana alternative oxidase AOX1a is …