Regulation and function of extracellular nicotinamide phosphoribosyltransferase/visfatin
…, A Vecchiè, M Casula, M Cea… - Comprehensive …, 2011 - Wiley Online Library
Nicotinamide phosphoribosyltransferase (NAMPT) is an adipokine‐enzyme, which was
described as to play bioactivities both in the intracellular and in the extracellular environment. …
described as to play bioactivities both in the intracellular and in the extracellular environment. …
[HTML][HTML] Nutrients in the Prevention of Alzheimer's Disease
Alzheimer’s disease (AD) is a disease caused by the complex interaction of multiple mechanisms,
some of which are still not fully understood. To date, pharmacological treatments and …
some of which are still not fully understood. To date, pharmacological treatments and …
Carfilzomib with cyclophosphamide and dexamethasone or lenalidomide and dexamethasone plus autologous transplantation or carfilzomib plus lenalidomide and …
…, M Grasso, S Ballanti, A Spadano, M Cea… - The Lancet …, 2021 - thelancet.com
… /m 2 was administered intravenously on days 1, 2, 8, 9, 15, and 16; lenalidomide 25 mg
administered orally on days 1–21; cyclophosphamide 300 mg/m 2 … Carfilzomib 36 mg/m 2 was …
administered orally on days 1–21; cyclophosphamide 300 mg/m 2 … Carfilzomib 36 mg/m 2 was …
Novel anti–B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma
… J6M0-mcMMAF specifically blocks cell growth via G 2 /M arrest and induces caspase 3–dependent
apoptosis in MM cells, alone and in coculture with bone marrow stromal cells or …
apoptosis in MM cells, alone and in coculture with bone marrow stromal cells or …
[HTML][HTML] Applications of electrospun nanofibers with antioxidant properties: A review
Antioxidants can be encapsulated to enhance their solubility or bioavailability or to protect
them from external factors. Electrospinning has proven to be an excellent option for …
them from external factors. Electrospinning has proven to be an excellent option for …
Fasting-mimicking diet and hormone therapy induce breast cancer regression
Approximately 75% of all breast cancers express the oestrogen and/or progesterone receptors.
Endocrine therapy is usually effective in these hormone-receptor-positive tumours, but …
Endocrine therapy is usually effective in these hormone-receptor-positive tumours, but …
CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications
The key nuclear export protein CRM1/XPO1 may represent a promising novel therapeutic
target in human multiple myeloma (MM). Here we showed that chromosome region …
target in human multiple myeloma (MM). Here we showed that chromosome region …
APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment
… (1-5) BM aspirates cultured with media (−, open column), M-CSF (M) (gray column), or M
with receptor activator of nuclear factor kappa-B ligand (M+R, black column). APRIL secretion is …
with receptor activator of nuclear factor kappa-B ligand (M+R, black column). APRIL secretion is …
US physician practices spend more than $15.4 billion annually to report quality measures
LP Casalino, D Gans, R Weber, M Cea… - Health …, 2016 - healthaffairs.org
Each year US physician practices in four common specialties spend, on average, 785 hours
per physician and more than $15.4 billion dealing with the reporting of quality measures. …
per physician and more than $15.4 billion dealing with the reporting of quality measures. …
Evaluation of biodegradable polymers as encapsulating agents for the development of a urea controlled-release fertilizer using biochar as support material
Biochar constitutes a promising support material for the formulation of controlled-release
fertilizers (CRFs). In this study we evaluated the effect of different polymeric materials as …
fertilizers (CRFs). In this study we evaluated the effect of different polymeric materials as …