The kynurenine pathway relates to post‐acute COVID‐19 objective cognitive impairment and PASC

…, A Kelleher, GJ Dore, GV Matthews… - Annals of Clinical …, 2023 - Wiley Online Library
Objective To determine the prevalence and natural history of post‐acute COVID‐19 objective
cognitive impairment and function, and their relationship to demographic, clinical factors, …

Post-acute COVID-19 cognitive impairment and decline uniquely associate with kynurenine pathway activation: a longitudinal observational study

…, C Phetsouphanh, A Kelleher, GJ Dore, GV Matthews… - Medrxiv, 2022 - medrxiv.org
Cognitive impairment and function post-acute mild to moderate COVID-19 are poorly
understood. We report findings of 128 prospectively studied SARS-CoV-2 positive patients. …

[HTML][HTML] Direct and indirect low skill fibre-optic intubation: A randomised crossover manikin study of six supraglottic airway devices

…, YR Tan, TGL Wong, VK Ho, AM Matthews… - Indian Journal of …, 2018 - journals.lww.com
Methods: Thirty anaesthetsiologists, 15 seniors and 15 juniors, each performed low skill FOI
(LSFOI) with seven SADs using both'direct'and'indirect'methods. The order of method and …

Comparison of four methods of predicting serum gentamicin concentrations in adult patients with impaired renal function.

DR Platt, SJ Matthews, MJ Sevka, JB Comer… - Clinical …, 1982 - europepmc.org
Four methods of predicting serum gentamicin concentrations (SGCs) in adult patients with
stable impaired renal function were compared. Serum samples obtained from 17 patients …

[HTML][HTML] The zebrafish reference genome sequence and its relationship to the human genome

…, S Humphray, K McLaren, L Matthews, S McLaren… - Nature, 2013 - nature.com
Zebrafish have become a popular organism for the study of vertebrate gene function 1 , 2 .
The virtually transparent embryos of this species, and the ability to accelerate genetic studies …

[HTML][HTML] Analyses of pig genomes provide insight into porcine demography and evolution

…, J Ma, O Madsen, K Mann, L Matthews, S McLaren… - Nature, 2012 - nature.com
For 10,000 years pigs and humans have shared a close and complex relationship. From
domestication to modern breeding practices, humans have shaped the genomes of domestic …

[HTML][HTML] Modernizing reference genome assemblies

…, R Fulton, L Matthews, S Whitehead, W Chow… - PLoS …, 2011 - journals.plos.org
The availability of a high quality human genome assembly has revolutionized biomedical
research. Genomics has now entered the realm of clinical genetics, with many groups using …

Noninvasive optical inhibition with a red-shifted microbial rhodopsin

AS Chuong, ML Miri, V Busskamp, GAC Matthews… - Nature …, 2014 - nature.com
Optogenetic inhibition of the electrical activity of neurons enables the causal assessment of
their contributions to brain functions. Red light penetrates deeper into tissue than other …

Human metabolic correlates of body mass index

SC Moore, CE Matthews, JN Sampson… - Metabolomics, 2014 - Springer
A high body mass index (BMI) is a major risk factor for several chronic diseases, but the
biology underlying these associations is not well-understood. Dyslipidemia, inflammation, and …

Metabolomics in epidemiology: sources of variability in metabolite measurements and implications

…, XO Shu, RZ Stolzenberg-Solomon, CE Matthews… - … , biomarkers & prevention, 2013 - AACR
Background: Metabolite levels within an individual vary over time. This within-individual
variability, coupled with technical variability, reduces the power for epidemiologic studies to …