User profiles for N. McPherson

NA McPherson

- Verified email at strath.ac.uk - Cited by 1798

Neil Macpherson

- Verified email at utoronto.ca - Cited by 1175

Peri-conception parental obesity, reproductive health, and transgenerational impacts

…, DL Zander-Fox, RL Robker, NO McPherson - Trends in Endocrinology …, 2015 - cell.com
Maternal over-nutrition during pregnancy is a risk factor for pregnancy complications and is
increasingly associated with adverse childhood outcomes such as increased propensity for …

Paternal obesity, interventions, and mechanistic pathways to impaired health in offspring

NO McPherson, T Fullston, RJ Aitken… - Annals of Nutrition and …, 2014 - karger.com
Background: The global rates of male overweight/obesity are rising, approaching 70% of the
total adult population in Western nations. Overweight/obesity increases the risk of chronic …

[HTML][HTML] Oxidative stress and reproductive function: reactive oxygen species in the mammalian pre-implantation embryo

…, L Pacella-Ince, MB Gonzalez, NO McPherson - …, 2022 - rep.bioscientifica.com
In brief Reactive oxygen species are generated throughout the pre-implantation period and
are necessary for normal embryo formation. However, at pathological levels, they result in …

[HTML][HTML] Application of laser in seam welding of dissimilar steel to aluminium joints for thick structural components

…, G Pardal, S Ganguly, S Williams, N McPherson - Optics and Lasers in …, 2015 - Elsevier
Laser welding-brazing technique, using a continuous wave (CW) fibre laser with 8000 W of
maximum power, was applied in conduction mode to join 2 mm thick steel (XF350) to 6 mm …

Preconception diet or exercise intervention in obese fathers normalizes sperm microRNA profile and metabolic syndrome in female offspring

NO McPherson, JA Owens… - American Journal of …, 2015 - journals.physiology.org
… Postmortem and metabolite data represent 7 females from 7 litters representing n = 6 HE
and n = 5 CC males and 8 females from 8 litters representing n = 7 HC and n = 6 HH and HCE …

[PDF][PDF] Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma

…, JA Mathers, L Becker, F Carneiro, N MacPherson… - Cancer cell, 2002 - cell.com
We report that human secretory breast carcinoma (SBC), a rare subtype of infiltrating ductal
carcinoma, expresses the ETV6-NTRK3 gene fusion previously cloned in pediatric …

Introduction of combined CHOP plus rituximab therapy dramatically improved outcome of diffuse large B-cell lymphoma in British Columbia

…, C Fitzgerald, K Gill, R Klasa, N MacPherson… - Journal of clinical …, 2005 - ascopubs.org
Purpose For more than two decades, cyclophosphamide, doxorubicin, vincristine, and
prednisone (CHOP) has been the standard therapy for diffuse large B-cell lymphoma (DLBCL). …

[HTML][HTML] Oxidative stress in mouse sperm impairs embryo development, fetal growth and alters adiposity and glucose regulation in female offspring

M Lane, NO McPherson, T Fullston, M Spillane… - PLoS …, 2014 - journals.plos.org
Paternal health cues are able to program the health of the next generation however the
mechanism for this transmission is unknown. Reactive oxygen species (ROS) are increased in …

Paternal obesity induces metabolic and sperm disturbances in male offspring that are exacerbated by their exposure to an “obesogenic” diet

T Fullston, NO McPherson, JA Owens… - Physiological …, 2015 - Wiley Online Library
n = 8 between treatment groups by either sacrifice for litters n … mice (F0 n = 9 represented
per F1 diet; ie, n = 4 CD F0, n = 5 … to either the same CD (n = 34 males) or HFD (n = 33 males; 1 …

[HTML][HTML] Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer

NR West, K Milne, PT Truong, N Macpherson… - Breast cancer …, 2011 - Springer
… We also examined the association between TIL and long-term chemotherapeutic efficacy
in a second cohort of ER-negative tumors (n = 255) with longer than 6 years of median follow-…