The drug efflux function of P-glycoprotein (P-gp) encoded by MDR1 can be influenced by
genetic polymorphisms, including two synonymous changes in the coding region of MDR1. …

The composition of the lipids of normal human bone marrow has been determined. Marrows
were obtained post-mortem from the femurs of 12 subjects ranging in age from 1 to 78 years…

In response to intracellular signals in Gram-negative bacteria, translational riboswitches—commonly
embedded in messenger RNAs (mRNAs)—regulate gene expression through …

Conventional techniques for detecting rare DNA sequences require many cycles of PCR
amplification for high sensitivity and specificity, potentially introducing significant biases and …

Over the last two decades, small interfering RNA (siRNA)-mediated gene silencing has
quickly become one of the most powerful techniques used to study gene function in vitro and a …

Self-assembled monolayers (SAMs) of single-stranded peptide nucleic acids (PNAs)
containing 3 to 7 thymine (T) nucleotides, a C-terminus cysteine, and an N-terminus ferrocene …

Bacteria live in a broad range of environmental temperatures that require adaptations of
their RNA sequences to maintain function. Riboswitches are regulatory RNAs that change …

" This case is about power...." I This incisive comment began Justice Stevens' dissenting
opinion in the recent Seminole Tribe case, but it would describe accurately any number of …

Ribosomal protein S1 plays important roles in the translation initiation step of many Escherichia
coli mRNAs, particularly those with weak Shine-Dalgarno sequences or structured 5′ …

Background Exposure to solar ultraviolet radiation is a well-known cause of skin cancer.
This is problematic for outdoor workers. In Denmark alone, occupational skin cancer poses a …